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Fmoc-L-Asn(lauryl)-OH
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-beta-lauryl-L-asparagine // Synonyms: Fmoc-Asn(dodecyl)-OH, N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-beta-dodecyl-L-asparagine, (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-(dodecylamino)-4-oxobutanoic acid,Fmoc-Asn(lauryl)-OH
- Product code:FAA7870
- CAS No.:843663-82-1
- Formula:C31H42N2O5
- Storage temperature:2-8°C
- Molecular weight:522.68 g/mol
from €220.00
description
Used for the synthesis of “reverse” peptide amphiphiles (PAs) with free N-termini. This amino acid modified with a fatty acid tail allows for the synthesis of this new class of PA molecules. They can assembled with complementary structures resulting in unusual thermal stability. This class of reverse PAs makes it possible to create biologically significant assemblies with free N-terminal peptide sequences, which were previously inaccessible, including those derived from phage display methodologies.
references
Coassembly of Amphiphiles with Opposite Peptide Polarities into Nanofibers. Heather A. Behanna, Jack J. J. M. Donners, Alex C. Gordon, Samuel I. Stupp; J. Am. Chem. Soc. 2005; 127(4): 1193-1200. DOI: 10.1021/ja044863u
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