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Fmoc-L-Cys(MDNPE)-OH
Chemical name: N-(((9H-fluoren-9-yl)methoxy)carbonyl)-S-(1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethyl)-L-cysteine // Synonyms: Fmoc-Cys(MDNPE), Fmoc-photo-caged cysteine, Fmoc-Cys(Methyl-o-nitropiperonyl), Fmoc-S-(Methyl-o-nitropiperonyl)-cysteine
- Product code:FAA7945
- Storage temperature:-20°C
- Formula:C27H24N2O8S
- Molecular weight:536.56 g/mol
- Purity :min.99%
from €407.00
description
This photocaged cysteine can be incorporated into peptides by SPPS and can be rapidly and efficiently photodeprotected to reveal the peptide.
references
Genetic Encoding of Photocaged Cysteine Allows Photoactivation of TEV Protease in Live Mammalian Cells; D. P. Nguyen, M. Mahesh, S. J. Elsässer, S. M. Hancock, C. Uttamapinant, J. W. Chin; J. Am. Chem. Soc. 2014; 136(6): 2240–2243. https://doi.org/10.1021/ja412191m
Spatio-Temporal Photoactivation of Cytotoxic Proteins; R. Cruz-Samperio, R. J. Mart, L. Y. P. Luk, Y.-H. Tsai, A. T. Jones, R. K. Allemann; ChemBioChem 2022; 23: e202200115. https://doi.org/10.1002/cbic.202200115
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