Fmoc-L-Cys(MDNPE)-OH

Chemical name: N-(((9H-fluoren-9-yl)methoxy)carbonyl)-S-(1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethyl)-L-cysteine // Synonyms: Fmoc-Cys(MDNPE), Fmoc-photo-caged cysteine, Fmoc-Cys(Methyl-o-nitropiperonyl), Fmoc-S-(Methyl-o-nitropiperonyl)-cysteine

  • Product code:FAA7945
  • Formula:C27H24N2O8S
  • Storage temperature:-20°C
  • Molecular weight:536.56 g/mol
  • Purity :min.99%

from €407.00

Grouped product items
Qty Packing unit Price SKU Availability
100 mg
€407.00
FAA7945.0100
<10 business days
250 mg
€678.00
FAA7945.0250
<10 business days
500 mg
€1,220.00
FAA7945.0500
<10 business days
1 g
€1,900.00
FAA7945.1000
Please inquire
description

This photocaged cysteine can be incorporated into peptides by SPPS and can be rapidly and efficiently photodeprotected to reveal the peptide.

references

Genetic Encoding of Photocaged Cysteine Allows Photoactivation of TEV Protease in Live Mammalian Cells; D. P. Nguyen, M. Mahesh, S. J. Elsässer, S. M. Hancock, C. Uttamapinant, J. W. Chin; J. Am. Chem. Soc. 2014; 136(6): 2240–2243. https://doi.org/10.1021/ja412191m

Spatio-Temporal Photoactivation of Cytotoxic Proteins; R. Cruz-Samperio, R. J. Mart, L. Y. P. Luk, Y.-H. Tsai, A. T. Jones, R. K. Allemann; ChemBioChem 2022; 23: e202200115. https://doi.org/10.1002/cbic.202200115

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