Fmoc-L-Api(6-CO2tBu,tBu)-OH

Chemical name: (S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)pimelic acid-6-t-butyloxycarbonyl-7-t-butyl ester // Synonyms: Fmoc-L-homohomoGla(OtBu)2-OH, (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-7-(tert-butoxy)-6-(tert-butoxycarbonyl)-7-oxoheptanoic acid, (S)-2-(Fmoc-amino)pimelic acid-6-t-butyloxycarbonyl-7-t-butyl ester, Fmoc-Api(6-CO2tBu,tBu)-OH

  • Product code:FAA8750
  • CAS No.:912354-10-0
  • Storage temperature:2-8°C
  • Formula:C31H39NO8
  • Molecular weight:553.65 g/mol

from €400.00

Grouped product items
Qty Packing unit Price SKU Availability
250 mg
€400.00
FAA8750.0250
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1 g
€1,200.00
FAA8750.1000
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description

Nonnatural amino acid analogue of L-gamma-carboxyglutamic acid (Gla), appropriately protected for Fmoc-based solid-phase peptide synthesis (SPPS). This derivative can be used in structure-activity relationship studies to replace Gla.


references

Reference:

Design and Concise Synthesis of Fully Protected Analogues of L-gamma-Carboxyglutamic Acid; S. Jiang, P. Li, C. C. Lai, J. A. Kelley, P. P. Roller; J. Org. Chem. 2006; 71(19): 7307-7314. https://doi.org/10.1021/jo061037q.

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