Boc-L-Thr[Psi(Me,Me)Pro]-OH

Chemical name: (4S,5R)-3-(tert-butyloxycarbonyl)-2,2,5-trimethyloxazolidine-4-carboxylic acid // Synonyms: Boc-Thr[Psi(Me,Me)Pro]-OH, N,O-Isopropylidene-N-tert-butoxycarbonyl-L-threonine

  • Product code:PSI1640
  • CAS No.:143364-85-6
  • Formula:C12H21NO5
  • Storage temperature:2-8°C
  • Molecular weight:259.30 g/mol
  • Purity :min. 99%
  • Enantiomeric Purity:min. 99,7%

from €70.00

Grouped product items
Qty Packing unit Price SKU Availability
1 g
€70.00
PSI1640.0001
<10 business days
5 g
€250.00
PSI1640.0005
Please inquire
25 g
€1,000.00
PSI1640.0025
Please inquire
description

Threonine-derived Pseudoproline monomer for SPPS. This building-block can be successfully coupled with many amino-acids using modern coupling techniques avoiding the need for pseudoproline dipeptides and giving the possibility to introduce pseudoprolines in peptides containing non-natural or rare amino-acids. See also the Fmoc-derivative FAA8695.


references

Reference:

Scope and limitations of pseudoprolines as individual amino acids in peptide synthesis; D. A. Senko, N. D. Timofeev, I. E. Kasheverov, I. A. Ivanov; Amino Acids 2021; 53: 665-671. https://doi.org/10.1007/s00726-021-02973-1.


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