Amino Acids

  1. Diazirine Amino Acids: Photocrosslinking Applications

    Two selected publications were summarized in this article in order to highlight the impressive utility of amino acids incorporating the diazirine photophore.

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  2. Fmoc-L-Lys(Nvoc)-OH

    o-Nitroveratryloxycarbonyl (Nvoc) is a photocleavable side chain protecting group for lysine that can be removed by irradiation with UV light (350 nm).

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  3. H-L-Lys(Suc)-OH*HCl

    Succinylation of proteins on the epsilon-amino group of lysine residues is a posttranslational modification that is still poorly understood.

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  4. Hydrolysis-Stable Mimics of Phosphorylated Amino Acids (Ser, Thr and Tyr)

    Phosphorylation of serine, threonine and tyrosine is counted among the most important posttranslational modifications that occur in organisms.

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  5. Diazirine Amino Acids for Photo Cross-Linkage in Living Cells

    Iris Biotech introduces a comprehensive set of photo-crosslinking amino acids bearing the diazirine moiety.

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  6. beta,beta-Dimethyl Amino Acids

    The use of bioactive peptides has increased over the recent years as they attracted attention for their use as therapeutic agents.

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  7. Fmoc-L-Cys(Propargyl)-OH

    This alkyne-functionalized cysteine building block can be incorporated into peptides via the Fmoc strategy.

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  8. Standard Fmoc Amino Acid Building Blocks

    Amino acids of high quality are crucial for the synthesis of peptides with a high purity.

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  9. Application of the Trt and Fmoc groups for the protection of polyfunctional α-amino acids

    Abstract: Ditrityl amino acids Trt-Lys(Trt)-OH (Trt = CPh3), Trt-Orn(Trt)-OH, Trt-Ser(Trt)-OH, and Trt-Hse(Trt)-OH were prepared and used in the synthesis of trityl-protected peptides, e.g., Trt-Ser(Trt)-Phe-NH2.

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  10. Triamino Acids

    Fmoc-L-Dap(2-Boc-aminoethyl)-OH is the first in a series of new triamino acid building blocks. This azalysine is useful for introducing positive charges into a peptide, or for creating branched structures.

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