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Blog - Amino Acids
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Net content and purity, two key parameters in peptide synthesis
What is the difference between net content and purity and why are both parameters so important for reliable experimental results? Read our blog for more details!
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PotM: Semaglutide and Peptide-Based Weight-Loss Drugs
The example of Semaglutide: Improve the pharmacokinetics of your therapeutic peptides by increasing their resistance against proteases via binding to plasma proteins.
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UAA! Discover Aminocoumarinyl Lysine
We say "UAA"! By genetic code expansion you can incorporate our novel aminocoumarinyl lysine in your favorite protein where it serves you as fluorescent probe or photo-activatable caged lysine.
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Discover TIQ and TIC as Proline Analogs
Implement our 1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (TIQ) and -3-carboxylic acid (TIC) building blocks as proline analogs! Shape your peptide and improve binding and performance!
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The Photosensitive MNI Protecting Group
Shining light on 4-methoxy-7-nitroindoline (MNI) photocaged aspartate and glutamate building blocks suitable for Fmoc-SPPS. Liberate the sidechain carboxylic acid by irradiation with UV-light of 365 nm.
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New Maillard Products for Peptide Synthesis and Analytics
Benefit of our latest Maillard Reaction Product additions! Use them as reference standard for quality control and food analysis or synthesize modified peptides for research studies.
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PotM: Furan-Crosslinking and 5HP2O as Maleimide Alternative
Game Changer for Protein Modification: Discover oxidation-induced furan crosslinking and 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones (5HP2Os) as stable alternative to maleimides.
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Chain Extension: Discover Homo Amino Acids
We expanded our portfolio of Fmoc-protected homo amino acids. Benefit of their unique properties to modulate the stability, hydrophobicity, and biological performance of your peptide!
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Hidden Champion – The Tetrahydropyranyl Protective Group
Tetrahydropyranyl (THP) is an excellent protective group for hydroxy and thiol moieties but rarely used in solid-phase peptide synthesis (SPPS). Discover its advantages, e.g., over O/StBu and Trt.
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Common Side Reactions in Fmoc Solid-Phase Peptide Synthesis
Collect information about the most common side reactions during Fmoc SPPS and how to avoid them! Choose your building blocks and conditions wisely to avoid unnecessary trouble!
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