Welcome to Iris Biotech
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Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying through a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.
Continue to Iris Biotech GmbHSend request to US distributorPublished on 29.01.2014
Compounds like putrescine, spermidine, and spermine play important roles in both eukaryotic and prokaryotic cells and show many other different biological functions. Most eukaryotic cells have a polyamine transporter system on their cell membrane that facilitates the internalization of exogenous polyamines. This system is highly active in rapidly proliferating cells and is the target of many sophisticated chemotherapeutics currently under development.
They also have been found to act as promoters of programmed ribosomal frame shifting during translation, as modulators of a variety of ion channels and receptors and play an important role in cell growth pathways. Participation in initiating the expression of SOS response of Colicin E7 operon, down-regulation of proteins that are essential for colicin E7 uptake, enhancing the permeability of the blood–brain barrier, binding to DNA as cations are only a few of many other biological functions and targets for drug development either as carrier or as structural key element.
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