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Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying through a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.
Continue to Iris Biotech GmbHSend request to US distributorChemischer Name: (2R)-2-amino-3-((1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethyl)selanyl)propanoic acid trifluoroacetate // Synonyme: 2235373-47-2 net, PSc, Photo-caged selenocysteine, H-sec(methyl-o-nitropiperonyl), Se-(methyl-o-nitropiperonyl)-selenocysteine,[(R,S)-1-[4',5'-(methylenedioxy)-2'-nitrophenyl]ethyl]-L-selenocysteine trifluoroacetate
Ab 324,00 €
Sec allows the site-specific covalent protein modification, even in the presence of native cysteine, as the reactivity of a selenol group exceeds that of a thiol group. This photocaged selenocysteine (PSc) is incorporated as an unnatural amino acid in response to an amber stop codon using a mutant pyrrolysyl-tRNA/tRNA synthetase pair. Decaging can be achieved by irradiation with UV light (365 nm).
Site-Specific Incorporation of Selenocysteine by Genetic Encoding as a Photocaged Unnatural Amino Acid; A. P. Welegedara, L. A. Adams, T. Huber, B. Graham, G. Otting; Bioconjugate Chem. 2018; 29(7): 2257-2264. https://doi.org/10.1021/acs.bioconjchem.8b00254.
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