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Continue to Iris Biotech GmbHSend request to US distributorChemischer Name: N-Benzyloxycarbonyl-aspartyl-glutamyl-valyl-aspartyl-Rh110-D-proline // Synonyme: Z-Asp-Glu-Val-Asp-Rhodamine(110)-D-Pro, substrate for caspase-3
Ab 1.210,00 €
This asymmetric Rhodamine 110 substrates for caspase-3 employs a simple and straight forward kinetics upon analysis. Absorption wave length 492 nm, emission wave length 529 nm. While the intact substrate is virtually non-fluorescent, fluorescence largely increases (approx.. 3500 fold) upon cleavage. Superior signal-to-noise ratio combined with high sensitivity. In Rh110 assays this substrate delivers much less false positive hits in synthetic product libraries than corresponding AMC (7-amino-4-methylcoumarin) substrates.
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S.P. Leytus et al.; Biochem. J. 1983; 209: 299-307.
S.P. Leytus et al.; Biochem. J. 1983; 209: 299-307.