Photo-Benzylamine*HCl

Chemischer Name: 4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzylamine hydrochloride // Synonyme: (4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)methanamine hydrochlorideComponent: CAS 400781-05-7

  • Art-Nr.:RL-2930
  • CAS Nr.:1258874-29-1
  • Formel:C9H8N3F3*HCl
  • Lagertemperatur:-20°C
  • Molare Masse:215,18*36,45 g/mol

Ab 250,00 €

Gruppiert Produkte - Artikel
Anzahl Verpackungsgröße Preis SKU Warenverfügbarkeit
200 mg
250,00 €
RL-2930.0200
<10 Arbeitstage
1 g
700,00 €
RL-2930.1000
<10 Arbeitstage
Sicherheitsdatenblätter
description

Nucleophilic photo cross-linker. The amine function can conjugate to electrophiles like carbonyl functions with standard reaction conditions. The diazirine ring will dismiss N2 under illumination of UV light and the remaining carbene will undergo insertion and addition reaction to any neighboring molecule and irreversibly form a covalent bond.


Shipping with dry ice required!

Transport costs depend on destination.

Please inquire!


references

Cross-linking chemistry and biology: development of multifunctional photoaffinity probes. Takenori Tomohiro, Makoto Hashimoto, Yasumaru Hatanaka; Chem. Record 2005; 5(6): 385-395. DOI: 10.1002/tcr.20058

Recent Progress in Diazirine-Based Photoaffinity Labeling. Makoto Hashimoto, Yasumaru Hatanaka; Eur. J. Org. Chem. 2008; 2513-2523. DOI: 10.1002/ejoc.200701069

Endeavors to Make the Photophore, Diazirine Easy to Use. Yutaka Sadakane; Yakugaku Zasshi 2007; 127(10): 1693-1699. DOI: org/10.1248/yakushi.127.1693

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis. James R. Hill, Avril A. B. Robertson; J. Med. Chem. 2018; 61: 6945−6963. DOI: 10.1021/acs.jmedchem.7b01561.


Benötigen Sie weitere Informationen über dieses Produkt?

kontaktieren Sie uns

Schneller Kontakt

Bitte senden Sie mir mehr Informationen über