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Boc-TfLeu-OH (4SR)
Chemical name: N-alpha-t-Butyloxycarbonyl-5,5,5-trifluoro-L-leucine (4SR) // Synonyms: (2S,4S)(2S,4R)-Boc-2-amino-5,5,5-trifluoro-4-methylpentanoic acid, (2S,4S)(2S,4R)-Boc-L-5,5,5-trifluoroleucine, Boc-L-Leu(F3)-OH (2S,4RS),(2S)-2-((tert-butoxycarbonyl)amino)-5,5,5-trifluoro-4-methyl pentanoic acid
- Product code:BAA4480
- CAS No.:343328-83-6
- Formula:C11H18F3NO4
- Molecular weight:285.26 g/mol
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references
Enzymatic N-terminal addition of noncanonical amino acids to peptides and proteins; R. E. Connor, K. Piatkov, A. Varshavsky and D. A. Tirrell; Chembiochem : a European journal of chemical biology 2008; 9: 366-9. https://doi.org/10.1002/cbic.200700605
Stabilization of coiled-coil peptide domains by introduction of trifluoroleucine; Y. Tang, G. Ghirlanda, N. Vaidehi, J. Kua, D. T. Mainz, I. W. Goddard, W. F. DeGrado and D. A. Tirrell; Biochemistry 2001; 40: 2790-6. https://doi.org/10.1021/bi0022588
Self-association and membrane-binding behavior of melittins containing trifluoroleucine; A. Niemz and D. A. Tirrell; J Am Chem Soc 2001; 123: 7407-13. https://doi.org/10.1021/ja004351p
Amino acids and peptides. XXIII. Leu-enkephalin analogs containing a fluorinated amino acid at position 2, 4 or 5; M. Maeda, K. Kawasaki, T. Taguchi, Y. Kobayashi, Y. Yamamoto, K. Shimokawa, M. Takahashi, K. Nakao and H. Kaneto; Chem Pharm Bull (Tokyo) 1994; 42: 1658-62. https://doi.org/10.1248/cpb.42.1658
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