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Fmoc-beta-Me-D-Ile-OH
Chemical name: (R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3,3-dimethylpentanoic acid // Synonyms: Fmoc-beta-Me-D-isoleucine, Fmoc-D-ß-methylisoleucine, (R)-2-(Fmoc-amino)-3,3-diMe-pentanoic acid, Fmoc-D-alpha-t-amylglycine
- Product code:FAA2625
- CAS No.:1310680-40-0
- Formula:C22H25NO4
- Storage temperature:2-8°C
- Molecular weight:367.44 g/mol
from $187.50
description
beta,beta-Dimethylation of amino acids stabilizes appropriate peptides towards digestion by proteases.
references
Total synthesis of the large non-ribosomal peptide polytheonamide B; Masayuki Inoue, Naoki Shinohara, Shintaro Tanabe, Tomoaki Takahashi, KenOkura, Hiroaki Itoh, Yuki Mizoguchi, Maiko Iida, Nayoung Lee and Shigeru Matsuoka; Nature Chem. 2010; 2: 281-285. DOI: 10.1038/nchem.554.
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