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Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying through a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.
Continue to Iris Biotech GmbHSend request to US distributorChemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-3-ethyl-L-norvaline // Synonyms: (S)-Fmoc-2-amino-3-ethyl-pentanoic acid, (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-ethylpentanoic acid, Fmoc-Nva(3-Et)-OH
from $375.00
Discovery of Begacestat, a Notch-1-Sparing g-Secretase Inhibitor for the Treatment of Alzheimer’s Disease. S. C. Mayer, A. F. Kreft, B. Harrison, M. Abou-Gharbia, M. Antane, S. Aschmies, K. Atchison, M. Chlenov, D. C. Cole, T. Comery, G. Diamantidis, J. Ellingboe, K. Fan, R. Galante, C. Gonzales, D. M. Ho, M. E. Hoke, Y. Hu, D. Huryn, U. Jain, M. Jin, K. Kremer, D. Kubrak, M. Lin, P. Lu, R. Magolda, R. Martone, W. Moore, A. Oganesian, M. N. Pangalos, A. Porte, P. Reinhart, L. Resnick, D. R. Riddell, J. Sonnenberg-Reines, J. R. Stock, S.-C. Sun, E. Wagner, T. Wang, K. Woller, Z. Xu, M. M. Zaleska, J. Zeldis, M. Zhang, H. Zhou, and J. S. Jacobsen; J. Med. Chem. 2008; 51: 7348-7351. https://doi.org/10.1021/jm801252w.
Synthesis and structure-activity relationship of a novel series of heterocyclic sulfonamide g-secretase inhibitors. J. Pu, A. F. Kreft, S. H. Aschmies, K. P. Atchison, J. Berkowitz, T. J. Caggiano, M. Chlenov, G. Diamantidis, B. L. Harrison, Y. Hu, D. Huryn. J. S. Jacobsen, M. Jin, K. Lipinski. P. Lu. R. L. Martone, K. Morris, J. Sonnenberg-Reines, D. R. Riddell, J. Sabalski, S.-C. Sun, E. Wagner, Y. Wang, Z. Xu, H. Zhou, and L. Resnick; Bioorg. Med. Chem. 2009; 17: 4708-4717. https://doi.org/10.1016/j.bmc.2009.04.052.
Structure-activity relationships of tubulysin analogues. J. R. Courter, J. Z. Hamilton, N. R. Hendrick, M. Zaval, A. B. Waight, R. P. Lyon, P. D. Senter, S. C. Jeffrey, and P. J. Burke; Bioorg. Med. Chem. Lett. 2020; 30: 127241. https://doi.org/10.1016/j.bmcl.2020.127241.
Peptide Macrocycle Inhibitor of Coagulation Factor XII with Subnanomolar Affinity and High Target Selectivity. S. J. Middendorp, J. Wilbs, C. Quarroz, S. Calzavarini, A. Angelillo-Scherrer, and C. Heinis; J. Med. Chem. 2017; 60: 1151-1158. https://doi.org/10.1021/acs.jmedchem.6b01548.
Structure-activity relationship study of the tumour-targeting peptide A20FMDV2 via modification of Lys16, Leu13, and N- and/or C-terminal functionality. K.-y. Hung, P. W. R. Harris, A. Desai, J. F. Marshall, and M. A. Brimble; Eur. J. Med. Chem. 2017; 136: 154-164. https://doi.org/10.1016/j.ejmech.2017.05.008.
Lead Optimization Yields High Affinity Frizzled 7-Targeting Peptides That Modulate Clostridium difficile Toxin B Pathogenicity in Epithelial Cells. S. Hansen, A. H. Nile, S. C. Mehta, J. Fuhrmann, and R. N. Hannoush; J. Med. Chem. 2019; 62: 7739-7750. https://doi.org/10.1021/acs.jmedchem.9b00500.
Peptidomimetic ethyl propenoate covalent inhibitors of the enterovirus 71 3C protease: a P2-P4 study. M. J. Ang, Q. Y. Lau, F. M. Ng, S. W. Then, A. Poulsen, Y. K. Cheong, Z. X. Ngoh, Y. W. Tan, J. Peng, T. H. Keller, J. Hill, J. J. Chu, and C. S. B. Chia; J. Enzyme Inhib. Med. Chem. 2016; 3: 332-339. https://doi.org/10.3109/14756366.2015.1018245.
Enhanced antimalarial activity of plasmepsin V inhibitors by modification of the P2 position of PEXEL peptidomimetics. W. Nguyen, A. N. Hodder, R. Bestel de Lezongard, P. E. Czabotar, K. E. Jarman, M. T. O’Neill, J. K. Thompson, H. J. Sabroux, A. F. Cowman, J. A. Boddey, B. E. Sleebs; Eur. J. Med. Chem. 2018; 154: 182-198. https://doi.org/10.1016/j.ejmech.2018.05.022.