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Fmoc-L-Aha-OH
Chemical name: (S)-2-(9-Fluorenylmethyloxycarbonylamino)-4-azidobutanoic acid // Synonyms: N-alpha-(9-Fluorenylmethyloxycarbonyl)-4-azido-L-homoalanine, L-2-(Fmoc-amino)-4-azidobutanoic acid, (2S)-4-azido-2-(Fmoc-amino)butanoic acid, Fmoc-azidohomoalanine,Fmoc-L-gamma-azidohomoalanine, Fm oc-L-Dab(N3)-OH, Fmoc-Dab(N3), Fmoc-AHA, Fmoc-Aha-
- Product code:FAA6620
- CAS No.:942518-20-9
- Formula:C19H18N4O4
- Storage temperature:2-8°C
- Molecular weight:366.41 g/mol
- Purity :min. 99%
- Enantiomeric Purity:min. 99.9%
from $90.00
description
Fmoc-Dab(N3) is incorporated into peptides that can be further selectively modified using Staudinger ligation or Click-chemistry. The azido-group can be reduced to give 2,4-diaminobutyric acid.
references
van Kasteren, Sander I.; Kramer, Holger B.; Jensen, Henrik H.; Campbell, Sandra J.; Kirkpatrick, Joanna; Oldham, Neil J.; Anthony, Daniel C.; Davis, Benjamin G. Nature (2007), 446(7139), 1105-1109. DOI:10.1038/nature05757;
Empting, Martin; Avrutina, Olga; Meusinger, Reinhard; Fabritz, Sebastian; Reinwarth, Michael; Biesalski, Markus; Voigt, Stephan; Buntkowsky, Gerd; Kolmar, Harald Angewandte Chemie, International Edition (2011), 50(22), 5207-5211. DOI:10.1002/anie.201008142;
Hatai, Joydev; Motiei, Leila; Margulies, David Journal of the American Chemical Society (2017), 139(6), 2136-2139. DOI:10.1021/jacs.6b10809.
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Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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