Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
USD
Quick contact
Please send me more information about
Fmoc-L-Dap(Ns)-OH
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-beta-nosyl-L-2,3-diaminopropionic acid // Synonyms: Fmoc-Dapa(Ns)-OH, Fmoc-Dpr(Ns)-OH, Fmoc-Dap(Ns), Fmoc-Dap(Ns)-OH, Fmoc-Dap(Nosyl), (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(2-nitrobenzenesulfonamido)propanoic acid,N-alpha-Fmoc-N-beta- Ns-L-2,3-diaminopropionic acid
- Product code:FAA7310
- CAS No.:867213-27-2
- Formula:C24H21N3O8S
- Storage temperature:2-8°C
- Molecular weight:511.50 g/mol
- Purity :min. 98%
- Enantiomeric Purity:min. 99.7%
from $100.00
description
Used as an orthogonally protected Dap building-block in SPPS. The Nosyl-group can be utilized to enable Mitsunobu-reaction or N-alkylations at the side-chain N atom.
references
Solid-Phase Synthesis of Amine-Bridged Cyclic Enkephalin Analogues via On-Resin Cyclization Utilizing the Fukuyama−Mitsunobu Reaction; Yosup Rew, Murray Goodman; J. Org. Chem. 2002; 67(25): 8820-8826. DOI: 10.1021/jo020447l.
Synthetic strategy for side chain mono-N-alkylation of Fmoc-amino acids promoted by molecular sieves. Monfregola L., De Luca S.; Amino Acids 2011; 41(4): 981-990. DOI: 10.1007/s00726-010-0798-6.
New synthetic strategy for o-NBS protected amino acids and their use in synthesis of mono-benzylated peptides; Stefano de Luca, Raffaella Della Moglie, Antonia De Capua, Giancarlo Morelli;
Tetrahedron Lett. 2005; 46(39): 6637-6640. DOI: 10.1016/j.tetlet.2005.07.154.
* Disclaimer
We refer to our general terms and conditions.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
Do you need further information about this product?
get in contact
We found other products you might like!
