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Fmoc-L-Tyr(Msib)-OH
Chemical name: (2S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-((4-(methylsulfinyl)benzyl)oxy)phenyl)propanoic acid // Synonyms: Fmoc-Tyr(Msib)-OH, (2S)-2-(Fmoc)-3-(4-((4-(methylsulfinyl)benzyl)oxy)phenyl)propanoic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-[[4-(methylsulfinyl)phenyl]methyl]-L-Tyrosine,N-Fmoc-O-[[4-(methyls ulfinyl)phenyl]methyl]-L-Tyrosine, safety catch Fm
- Product code:FAA7885
- CAS No.:156125-68-7
- Formula:C32H29NO6S
- Storage temperature:2-8°C
- Molecular weight:555.65 g/mol
from $1,125.00
description
A Fmoc protected L-Tyrosine for SPSS, with an Msib protected phenolic hydroxyl group. The Msib protecting group is removed by reduction of the sulfoxide, followed by acidolysis with TFA.
references
Solid-Phase Peptide Synthesis Using a Four-Dimensional (Safety-Catch) Protecting Group Scheme; S. Noki, E. Brasil, H. Zhang, T. Bruckdorfer, B. de la Torre, F. Albericio; J. Org. Chem. 2022; 87(15): 9443–9453. https://doi.org/10.1021/acs.joc.2c01056
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Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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