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Fmoc-L-Phe(4-Eth)-OH
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-4-ethynyl-L-phenylalanine // Synonyms: Fmoc-4-Ethynyl-L-phenylalanine, Fmoc-Phe(4-Eth)-OH, Fmoc-4-Ethynyl-phenylalanine, (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-ethynylphenyl)propanoic acid,Fmoc-Phe(4-Eth)-OH, Fmoc-p-Ethyn yl-L-phenylalanine, Fmoc-p-Ethynyl-phenylalanine,
- Product code:FAA8530
- CAS No.:1228049-41-9
- Formula:C26H21NO4
- Storage temperature:-20°C
- Molecular weight:411.46 g/mol
from $812.50
description
This Fmoc-protected non canonical substituted phenylalanine contains a chemical handle, e.g. for post-translational biorthogonal conjugation reactions, e.g. by copper(I)-catalyzed azide-alkyne cycloadditions (CuAAC), an efficient Click Chemistry Reaction. CuAAC is orthogonal in the context of proteins and other cellular components, enabling applications in bacteria and mammalian cell lines.
references
An unnatural amino acid that mimics phosphotyrosine; J. Ge, H. Wu, S. Q. Yao; Chem. Comun. 2010; 46: 2980-2982. https://doi.org/10.1039/C000283F.
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