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H-L-Tyr(All)-OH
Chemical name: O-Allyl-L-tyrosine // Synonyms: O-Allyl-tyrosine, Tyr(All), (S)-3-(4-(allyloxy)phenyl)-2-aminopropanoic acid , H-Tyr(All)-OH
- Product code:HAA7435
- CAS No.:107903-42-4
- Formula:C12H15NO3
- Molecular weight:221.25 g/mol
- Purity :min. 99%
- Enantiomeric Purity:min. 99,7%
from $111.25
description
This non-canonical amino acid can be incorporated into proteins using mutant pyrrolysyl-tRNA synthetase–tRNAPylCUA pairs and can be used e.g. to identify protein tyrosine phosphatases.
references
Proteomic Identification of Protein Tyrosine Phosphatase and Substrate Interactions in Living Mammalian Cells by Genetic Encoding of Irreversible Enzyme Inhibitors; Hongting Tang, Zhen Dai, Xuewen Qin, Wenkang Cai, Liming Hu, Yujia Huang, Wenbing Cao, Fan Yang, Chu Wang, Tao Liu; J. Am. Chem. Soc. 2018; 140(41): 13253-13259. DOI: 10.1021/jacs.8b06922.
Exploring the potential impact of an expanded genetic code on protein function; Han Xiao, Fariborz Nasertorabi, Sei-hyun Choi, Gye Won Han, Sean A. Reed, Raymond C. Stevens, and Peter G. Schultz; PNAS 2015; 112(22): 6961-6966. DOI: 10.1073/pnas.1507741112.
Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes; Yan-Jiun Lee, Yadagiri Kurra, Yanyan Yang, Jessica Torres-Kolbus, Alexander Deiters, Wenshe R. Liu; Chem. Commun. 2014; 50: 13085-13088. DOI: 10.1039/C4CC06435F.
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