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H-L-Tyr(Clt)-2CT Resin
Chemical name: H-L-Tyr(Clt)-2-chlorotrityl resin // Synonyms: H-Tyr(Clt)-2CT Resin
- Product code:RAA1290
- Storage temperature:-20°C
- Particle size :100-200 mesh
- DVB crosslinking :1% DVB
- Loading:> 0.4 mmol/g
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description
The Clt (2-chlorotrityl) protecting group can selectively be removed by treatment with 1% TFA in dichloromethane and silane scavenger. The partially deprotected amino acid can be used for further derivatization, like phosphorylation, sulfonation, PEGylation, or conjugation with glycol building blocks or dyes.
references
Aletras A., Barlos K. et al; Int. J. Pept. Protein Res. 1995; 45(5): 488-496.
Barlos K. et al; Int. J. Pept. Protein Res. 1991; 38(6): 555-561.
Sarah L.M. et al, in „Fmoc Solid Phase Synthesis. A practical approach“, Ed.: Chan W.C., White P.D. Oxford University Press 2000, page 177.
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