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BDMT
Chemical name: 1,4-phenylenedimethanethiol, 1,4-Bis(mercaptomethyl)benzene // Synonyms: 1,4-phenylenedimethanethiol, 1,4-Bis(mercaptomethyl)benzene
- Product code:RL-3885
- CAS No.:105-09-9
- Formula:C8H10S2
- Molecular weight:170.29 g/mol
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description
1,4-Benzenedimethanethiol is used as thiol scavenger during solid-phase peptide synthesis. 1,4-BDMT is reported to afford the peptide in higher quality than standard aliphatic thiol reagents. Besides, in contrast to other thiol scavengers, this reagent is odorless.
references
1,4-Benzenedimethanethiol (1,4-BDMT) as a scavenger for greener peptide resin cleavages; J. Pawlas, T. Svensson, J. H. Rasmussen; RSC Adv. 2019; 9: 38928. https://doi.org/10.1039/c9ra08553j
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