Chemical name: (((2,7-disulfo-9H-fluoren-9-yl)methoxy)carbonyl)-L-isoleucine potassium salt // Synonyms: potassium 9-(((((1S,2S)-1-carboxy-2-methylbutyl)carbamoyl)oxy)methyl)-7-sulfonato-9H-fluoren-2-yl sulfite, Smoc-Ile-OH

  • Product code:SAA1030
  • CAS No.:2337407-24-4 (net)
  • Formula:C21H21K2NO10S2
  • Molecular weight:589.71 g/mol

Starting at $37.50

Grouped product items
Qty Packing unit Price SKU
5 g
10 g
Safety Data Sheets

Building blocks for aqueous solid-phase peptide synthesis (ASPPS). The 2,7-disulfo-9-fluorenylmethoxycarbonyl (Smoc) protecting group allows peptide synthesis using water instead of organic solvents – finally combining sustainability with cost optimization. The building blocks possess significant stability in basic aqueous solutions, but are easily losing their amino terminal protection upon mild treatment with particular water-soluble bases, e.g. NaOH, NH3, piperazine or ethanolamine. For ASPPS, a water-compatible resin, e.g. Tentagel, ChemMatrix, is required.


Method for peptide synthesis and apparatus for carrying out a method for solid phase synthesis of peptides; S. Knauer, T. M. L. Roese, O. Avrutina, H. Kolmar, C. Uth; 2016, WO 2016 050764.

Sustainable Peptide Synthesis Enabled by a Transient Protecting Group; S. Knauer, N. Koch, C. Uth, R. Meusinger, O. Avrutina, H. Kolmar; Angew. Chem. Int. Ed. 2020; 59(31): 12984-12990.

Improved method for preparing peptides; S. Knauer; WO 2019 101939.

Method for preparing peptides; S. Knauer; WO 2019 101940.

Bulk or large quantity order?

Do you need larger quantities for your development or production?

Do you need further information about this product?

get in contact

Quick contact

Please send me more information about

We found other products you might like!