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Fmoc-Ddax-L-Ala-OH
Nom chimique: N-alpha-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-6-((9-fluorenylmethyloxycarbonyl)amino)hexyl)-L-alanine // Synonymes: Fmoc-Ddax-Ala, Fmoc-Ddax-Ala-OH, (2S)-2-{[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexyl]amino}propanoic acid
- n° Art.:FAA8435
- n° CAS:2576507-90-7
- Formule:C32H38N2O6
- Storage temperature:2-8°C
- Masse moléculaire:546,65 g/mol
- Pureté:min. 99%
- Pureté Énantiomérique:min. 99,7%
from 234,00 €
description
Used as an Alanine-containing next-generation traceless "helping hand" solubilizing tag in SPPS. This solves the low reactivity issue of the tag with a peptide. Several Lysine residues are attached to this linker using Fmoc-SPPS. The solubilising tag can be removed with 1M hydrazine or hydroxylamine solution.
references
Chemical synthesis of Shiga toxin subunit B using a next-generation traceless “helping hand” solubilizing tag; J. M. Fulcher, M. E. Petersen, R. J. Giesler, Z. S. Cruz, D. M. Eckert, J. N. Francis, E. M. Kawamoto, M. T. Jacobsen, and M. S. Kay; Org Biomol Chem. 2019; 17; 10237-10244. https://doi.org/10.1039/C9OB02012H
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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