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Fmoc-Aca-DIM
Nom chimique: 6-((9-Fluorenylmethyl)oxycarbonylamino)-1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-hexan-1-ol // Synonymes: Fmoc-Ddax-OH, (9H-fluoren-9-yl)methyl N-[6-(4,4-dimethyl-2,6- dioxocyclohexylidene)-6-hydroxyhexyl]carbamate
- n° Art.:RL-3260
- n° CAS:2379561-08-5
- Formule:C29H33NO5
- Storage temperature:-20°C
- Masse moléculaire:475,58 g/mol
- Pureté:min. 98%
from 120,00 €
description
Used as a next-generation traceless "helping hand" solubilizing tag in SPPS. Several Lysine residues are attached to this linker using Fmoc-SPPS. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution. This linker is more stable than its predecessor Fmoc-Ddae-OH.
references
Chemical synthesis of Shiga toxin subunit B using a next-generation traceless "helping hand" solubilizing tag; J. M. Fulcher, M. E. Petersen, R. J. Giesler, Z. S. Cruz, D. M. Eckert, J. N. Francis, E. M. Kawamoto, M. T. Jacobsen and M. S. Kay; Org Biomol Chem 2019; 17: 10237-10244. https://doi.org/10.1039/c9ob02012h
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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