Halo-PEG(4)-Azide

Nom chimique: 1-Azido-18-chloro-3,6,9,12-tetraoxaoctadecane

  • n° Art.:RL-3710
  • n° CAS:2989398-83-4
  • Formule:C14H28ClN3O4
  • Storage temperature:-20°C
  • Masse moléculaire:337,85 g/mol

from 150,00 €

Grouped product items
Nombre Unité de vente Prix SKU Disponibilité
100 mg
150,00 €
RL-3710.0100
<10 jour ouvrables
250 mg
300,00 €
RL-3710.0250
<10 jour ouvrables
1 g
900,00 €
RL-3710.1000
<10 jour ouvrables
5 g
3 600,00 €
RL-3710.5000
<10 jour ouvrables
Fiches de données de sécurité
description

This chloroalkane linker serves as ligand for a specific modified bacterial haloalkane dehalogenase. This is a reporter protein whose sequence can easily be fused to a gene of interest. The reaction between the chloroalkane linker and the enzyme is fast and irreversible under physiological conditions and the system has been used extensively to measure protein-protein interactions in cells.

Furthermore, the additional azide moiety serves clickable moiety.


references

HaloTag technology: a versatile platform for biomedical applications; C. G. England, H. Luo and W. Cai; Bioconjug Chem 2015; 26: 975-86. https://doi.org/10.1021/acs.bioconjchem.5b00191.


HaloTag: a novel protein labeling technology for cell imaging and protein analysis; G. V. Los, L. P. Encell, M. G. McDougall, D. D. Hartzell, N. Karassina, C. Zimprich, M. G. Wood, R. Learish, R. F. Ohana, M. Urh, D. Simpson, J. Mendez, K. Zimmerman, P. Otto, G. Vidugiris, J. Zhu, A. Darzins, D. H. Klaubert, R. F. Bulleit and K. V. Wood; ACS Chem Biol 2008; 3: 373-382. https://doi.org/10.1021/cb800025k.

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