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Alkyne-PEG(5)-SNAP
Nom chimique: N-(4-(((2-amino-9H-purin-6-yl)oxy)methyl)benzyl)-4,7,10,13,16-pentaoxanonadec-18-ynamide // Synonymes: Alkyne-PEG(5)-Benzylguanine, Alkyne-PEG-Benzylguanine, Alkyne-PEG-SNAP, Alkyne-PEG(5)-BG, Alkyne-PEG-BG
- n° Art.:RL-3940
- Formule:C27H36N6O7
- Storage temperature:2-8°C
- Masse moléculaire:556,62 g/mol
from 300,00 €
description
Alkyne conjugated benzylguanine (BG). The BG moiety reacts specifically and rapidly with the so-called SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation.
The additional PEG moiety increases overall solubility.
references
Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand; J. Broichhagen, A. Damijonaitis, J. Levitz, K. R. Sokol, P. Leippe, D. Konrad, E. Y. Isacoff, D. Trauner; ACS Cent Sci. 2015; 1(7): 383-93. https://doi.org/10.1021/acscentsci.5b00260
A Semisynthetic Fluorescent Sensor Protein for Glutamate; M. A. Brun, K.-T. Tan, R. Griss, A. Kielkowska, L. Reymond, K. Johnsson; J. Am. Chem. Soc. 2012; 134(18): 7676-7678. https://doi.org/10.1021/ja3002277
Fura-2FF-based calciumindicator for proteinlabeling; A. A. Ruggiu, M. Bannwarth, K. Johnsson; Org. Biomol. Chem. 2010; 8: 3398-3401. https://doi.org/10.1039/C000158A
Indo-1 Derivatives for Local Calcium Sensing; M. Bannwarth, I. R. Corrêa Jr., M. Sztretye, S. Pouvreau, C. Fellay, A. Aebischer, L. Royer, E. Ríos, K. Johnsson; ACS Chem. Biol. 2009; 4(3): 179-190. https://doi.org/10.1021/cb800258g
Caged Substrates for Protein Labeling and Immobilization; S. Banala, A. Arnold, K. Johnsson; ChemBioChem 2008; 9(1): 38-41. https://doi.org/10.1002/cbic.200700472
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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