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Azide-SNAP
Nom chimique: N-(4-(((2-amino-9H-purin-6-yl)oxy)methyl)benzyl)-6-azidohexanamide // Synonymes: Azide-Benzylguanine, Azide-BG
- n° Art.:RL-3950
- Formule:C19H23N9O2
- Storage temperature:-20°C
- Masse moléculaire:409,45 g/mol
from 200,00 €
description
Azide conjugated benzylguanine (BG). The BG moiety reacts specifically and rapidly with the so-called SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional azide functionality suitable for further conjugation via Click Chemistry.
references
Yeast Three-Hybrid Screening for Identifying Anti-Tuberculosis Drug Targets; S. Moser, K. Johnsson; ChemBioChem 2013; 14(17): 2239-2242. https://doi.org/10.1002/cbic.201300472
A yeast-based screen reveals that sulfasalazine inhibits tetrahydrobiopterin biosynthesis; C. Chidley, H. Haruki, M. Grønlund Pedersen. E. Muller, K. Johnsson; Nat. Chem. Biol. 2011; 7: 373-383. https://doi.org/10.1038/nchembio.557
Caged Substrates for Protein Labeling and Immobilization; S. Banala, A. Arnold, K. Johnsson; ChemBioChem 2008; 9(1): 38-41. https://doi.org/10.1002/cbic.200700472
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