Blog - Amino Acids - Page 8

  1. Product of the Month: Fluorinated Amino Acids

    One approach for the design of bioactive peptides with improved pharmacological properties is the derivatization of amino acid building blocks with fluorine. Find out more about the advantages of fluorinated peptides.

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  2. Nitrodibenzofuran (NDBF) based Photocleavable Protecting Groups

    Nitrodibenzofuran (NDBF) is a photocleavable side chain protecting group that can be removed by photolysis upon irradiation with UV-light or – especially for in vivo applications – by two-photon excitation using near infrared light.

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  3. Product Focus: Next Generation Phosphoamino Acid Analogs

    Iris Biotech presents the next-generation of hydrolysis-stable phosphono-analogs of pSer, pThr and pTyr. Fluorination renders the phosphonic acid more acidic and thus an even better mimic of the parent phosphoamino acid.

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  4. Product Focus: Arginine Derivatives

    Looking to optimize or functionalize your peptide? Explore our ever-growing selection of Arg derivatives and find the one suitable for your application.

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  5. Product of the Month: Novel Fmoc-Amino Acids for Convenient Access to HDAC Inhibitors

    Find out more about those building blocks with side chains able to coordinate metal ions, and why peptide-based HDACis are intriguing synthetic targets.

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  6. Alkyne Amino Acids for Click Chemistry and other Conjugations:

    Alkyne amino acids allow for Click conjugations and other types of chemistry. Read more about alkyne-functionalized amino acids and our related products.

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  7. L-Cysteine from non-human/non-animal origin

    Iris Biotech offers L-Cysteine Hydrochloride Monohydrate from Cystine, which is produced by fermentation of Escherichia coli.

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  8. Phenyl-, Cyclohexyl- and BCP-Amino Acids

    Sidechain-derivatized amino acids have shown great potential in enhancing select properties of peptide lead compounds. Find the most recent additions to our portfolio of amino acids bearing additional aryl and alkyl groups in their side chains.

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  9. Lipidated Amino Acids

    The tremendous success of Liraglutide and Semaglutide has moved amino acids modified with lipids into the focus of many research endeavors. Delve into the treasure trove of our lipidated amino acids!

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  10. PotM: Bicyclo[1.1.1]pentanes as Phenyl Ring Bioisosteres

    The presence of phenyl groups in APIs is connected with various disadvantages. An increasingly popular solution is the use of BCP as a phenyl ring bioisostere. Find out more about this highly diversifiable motif.

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