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Fmoc-L-Lys(Dde)-OH
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-L-lysine // Synonyms: N-alpha-Fmoc-N-epsilon-Dde-L-lysine, Fmoc-Lys(Dde)-OH
- Product code:FAA1390
- CAS No.:150629-67-7
- Formula:C31H36N2O6
- Storage temperature:2-8°C
- Molecular weight:532.64 g/mol
- Purity :min. 98%
- Enantiomeric Purity:min. 99.7%
from €166.00
description
Building block with side protection orthogonal to Fmoc/tBu strategy. Can be used for side specific derivatization, for example for TFA mediated in situ cyclization, which is taking advantage of intermediate aspartamide formation.
references
A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage; Koushik Chandra, Tapta Kanchan Roy, Deborah E. Shalev, Abraham Loyter, Chaim Gilon, R. Benny Gerber, and Assaf Friedler; Angew. Chem. Int. Ed. 2014; 53: 9450-9455. DOI: 10.1002/anie.201402789.
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Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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