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Fmoc-D-Lys(Dde)-OH

Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-[(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl]-D-lysine // Synonyms: N-alpha-Fmoc-N-epsilon-Dde-D-lysine, Fmoc-D-Lys(Dde)

  • Product code:FAA1486
  • CAS No.:333973-51-6
  • Storage temperature:2-8°C
  • Formula:C31H36N2O6
  • Molecular weight:532.64 g/mol
  • Purity :min. 99%
  • Enantiomeric Purity:min. 99,7%

from €70.00

Grouped product items
Qty Packing unit Price SKU Availability
1 g
€70.00
FAA1486.0001
<10 business days
5 g
€250.00
FAA1486.0005
<10 business days
25 g
€1,000.00
FAA1486.0025
<10 business days
Safety Data Sheets
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description

Building block with side protection orthogonal to Fmoc/tBu strategy. Can be used for side specific derivatization, for example for TFA mediated in situ cyclization, which is taking advantage of intermediate aspartamide formation.

references

A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage; Koushik Chandra, Tapta Kanchan Roy, Deborah E. Shalev, Abraham Loyter, Chaim Gilon, R. Benny Gerber, and Assaf Friedler; Angew. Chem. Int. Ed. 2014; 53: 9450-9455. DOI: 10.1002/anie.201402789.

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