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Fmoc-L-Ser(TBDMS)-OH

Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-(t-butyl-dimethyl-silyl)-L-serine // Synonyms: Fmoc-Ser(TBDMS)-OH, Fmoc-Ser(BSi)-OH

  • Product code:FAA6510
  • CAS No.:146346-81-8
  • Storage temperature:2-8°C
  • Formula:C24H30NO5Si
  • Molecular weight:441.60 g/mol

from €230.00

Grouped product items
Qty Packing unit Price SKU Availability
1 g
€230.00
FAA6510.0001
<10 business days
5 g
€460.00
FAA6510.0005
11-20 business days
Safety Data Sheets
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description

The TBDMS protecting group of the serine hydroxy function is more labile towards TFA than tBu and can selectively be cleaved in the presence of Boc/tBu with tetrabutylammonium fluoride in DMF. However, Fmoc is also being removed under these conditions!

references

Fischer P.M.; Tetrahedron Lett. 1992; 33: 7605.

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