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TBTA
Chemical name: Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine
- Product code:RL-2010
- CAS No.:510758-28-8
- Formula:C30H30N10
- Storage temperature:-20°C
- Molecular weight:530.63 g/mol
from €300.00
description
Tris(benzyltriazolylmethyl)amine (TBTA) is stabilizing copper(I) towards oxidation in solution by forming a complex and catalyzes effectively quantitative, regioselective Huisgen 1,3-dipolar cycloadditions between alkynes and azides (the so called 'click' cycloaddition reaction), in a variety of aqueous and organic solvents. In the literature, it has been gaining widespread use as a biochemical tool for the tagging of proteins and enzymes.
references
Polytriazoles as copper(I)-stabilizing ligands in catalysis; T. R. Chan, R. Hilgraf, K. B. Sharpless and V. V. Fokin; Org Lett 2004; 6: 2853-5. https://doi.org/10.1021/ol0493094
'Click' cycloaddition catalysts: copper(I) and copper(II) tris(triazolylmethyl)amine complexes; P. S. Donnelly, S. D. Zanatta, S. C. Zammit, J. M. White and S. J. Williams; Chem Commun (Camb) 2008: 2459-61. https://doi.org/10.1039/b719724a
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Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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