TBTA

Chemical name: Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine

  • Product code:RL-2010
  • CAS No.:510758-28-8
  • Formula:C30H30N10
  • Molecular weight:530.63 g/mol

from €240.00

Grouped product items
Qty Packing unit Price SKU Availability
1 g
€240.00
RL-2010.1000
<10 business days
5 g
€700.00
RL-2010.5000
<10 business days
description

Tris(benzyltriazolylmethyl)amine (TBTA) is stabilizing copper(I) towards oxidation in solution by forming a complex and catalyzes effectively quantitative, regioselective Huisgen 1,3-dipolar cycloadditions between alkynes and azides (the so called 'click' cycloaddition reaction), in a variety of aqueous and organic solvents. In the literature, it has been gaining widespread use as a biochemical tool for the tagging of proteins and enzymes.

references

Polytriazoles as copper(I)-stabilizing ligands in catalysis; T. R. Chan, R. Hilgraf, K. B. Sharpless and V. V. Fokin; Org Lett 2004; 6: 2853-5. https://doi.org/10.1021/ol0493094

'Click' cycloaddition catalysts: copper(I) and copper(II) tris(triazolylmethyl)amine complexes; P. S. Donnelly, S. D. Zanatta, S. C. Zammit, J. M. White and S. J. Williams; Chem Commun (Camb) 2008: 2459-61. https://doi.org/10.1039/b719724a


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