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Blog
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PotM: Guanidino-Proline as rigid Arginine mimic
Interested in structure activity studies on your Arginine containing peptide or further optimization for improved receptor binding? Explore our guanidino Proline derivatives as rigid Arginine mimics.
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Celebrating 20 Years of Peptide Innovation
Hurrah! We are celebrating our 20th anniversary with a refreshed company logo. Interested in the evolution behind? Click here to find out more!
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Fmoc-MeDbz-OH – Available on Large Scale
Are you using the Fmoc-MeDbz-OH Dawson Linker in large scale on a regular basis? A robust and economic processallows us to promptly provide you with kg quantities at competitive prices and in high quality.
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DACNs for Strain-Promoted Azide-Alkyne Cycloadditions (SPAAC)
Herein we present substituted diazacyclononynes (DACNs) as versatile tools for metal-free strain-promoted Click Chemistry that are characterized by high reactivity and stability, both thermally and chemically.
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PotM: Asp(CSY) – Tackling Aspartimide Formation
Fmoc-Asp(CSY)-OH – an innovative building block to suppress aspartimide formation during peptide synthesis by utilizing cyanosulfurylide as carboxylic acid protecting group. Read on to find our more!
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Adamantyls are a Chemist’s Best Friend
The highly lipophilic, bulky adamantyl motif is a promising and validated building block to increase the drug-qualities of lead compounds without increasing their toxicity.
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Ramage Linker
An efficient, versatile linker developed for the synthesis of C-terminal primary/secondary amides and hydrazides as well as peptide alcohols, which is compatible with SPPS and suppresses side reactions.
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Aminooxy-Amino Acid Derivatives
Herein, we present aminooxy-amino acids reported for peptide synthesis via oxime ligation, cyclization via oxime formation, derivatization e.g. by glycosylation, or chelation. Read on to find out more.
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