Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Währung
EUR
Schneller Kontakt
Bitte senden Sie mir mehr Informationen über
Fmoc-3-amino-2-(adamantan-1-yl)-propionic acid
Chemischer Name: 3-(9-Fluorenylmethyloxycarbonyl)-amino-2-(adamantan-1-yl)-propionic acid // Synonyme: 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-((3r,5r,7r)-adamantan-1-yl)propanoic acid, (R,S)-Fmoc-3-amino-2-(adamantan-1-yl)-propionic acid
- Art-Nr.:FAA8525
- Lagertemperatur:2-8°C
- Formel:C28H31NO4
- Molare Masse:445,56 g/mol
Ab auf Anfrage
description
The highly lipophilic, symmetrical adamantly motif is reported for its hydrophobic bulk and spherical shape, proposed by modelling to favor hydrophobic contacts in protein binding pockets. Thus, this adamantane building block can be used for structure-activity-relationship studies. Furthermore, adamantane is part of various medicinally important compounds.
references
Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor D; A. Vulpetti, N. Ostermann, S. Randl. T. Yoon, A. M. Sweeney, F. Cumin, E. Lorthiois, S. Rüdisser, P. Erbel, J. Maibaum; ACS Med. Chem. Lett. 2018; 9(5): 490-495. https://doi.org/10.1021/acsmedchemlett.8b00104.
Towards a Novel Class of Multitarget-Directed Ligands: Dual P2X7-NMDA Receptor Antagonists; O. Karoutzou, S.-H. Kwak, S.-D. Lee, D. Martínez-Falguera, F. X. Sureda, S. Vázquez, Y.-C. Kim, M. Barniol-Xicota; Molecules 2018; 23(1): 230. https://doi.org/10.3390/molecules23010230.
Benötigen Sie weitere Informationen über dieses Produkt?
kontaktieren Sie uns
Produkte, die Sie auch interessieren könnten!
