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Fmoc-L-Lys(Mmt)-OH
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-4-methoxytrityl-L-lysine // Synonyms: Fmoc-Lys(Mmt)-OH
- Product code:FAA1622
- CAS No.:159857-60-0
- Formula:C41H40N2O5
- Storage temperature:-20°C
- Molecular weight:640.77 g/mol
from $212.50
description
Building block with side protection orthogonal to Fmoc/tBu strategy. Can be used for side specific derivatization, for example for TFA mediated in situ cyclization, which is taking advantage of intermediate aspartamide formation.
references
A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage; Koushik Chandra, Tapta Kanchan Roy, Deborah E. Shalev, Abraham Loyter, Chaim Gilon, R. Benny Gerber,
and Assaf Friedler; Angew. Chem. Int. Ed. 2014; 53: 9450-9455. DOI: 10.1002/anie.201402789.
Solid phase strategies: Applications of 2-acetyl-4-nitroindane-1,3-dione as a selective protecting group for primary amines; B. Kellam, B. W. Bycroft, W. C.Chan and S. R. Chhabra; Tetrahedron 1998; 54: 6817-6832. doi:http://dx.doi.org/10.1016/S0040-4020(98)00365-2
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Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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