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Fmoc-L-Lys(Msz)-OH
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-(4-methylsulfinyl-benzyloxycarbonyl)-L-lysine // Synonyms: Safety-Catch L-Lysine
- Product code:FAA9100
- CAS No.:2919325-14-5
- Formula:C30H32N2O7S
- Storage temperature:2-8°C
- Molecular weight:564.65 g/mol
from $1,125.00
description
Orthogonal safety catch protecting group that is stable under standard cleavage conditions, including the TFA treatment that removes the tBu-based groups. This new concept of protecting groups can facilitate the synthesis and manipulation of difficult peptides.
references
Solid-Phase Peptide Synthesis Using a Four-Dimensional (Safety-Catch) Protecting Group Scheme; S. Noki, E. Brasil, H. Zhang, T. Bruckdorfer, B. de la Torre, F. Albericio; J. Org. Chem. 2022, 87(15): 9443-9453. https://doi.org/10.1021/acs.joc.2c01056
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