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Fmoc-L-Lys(Heptanoyl)-OH
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-heptanoyl-L-lysine // Synonyms: Fmoc-Lys(Heptanoyl)-OH, Fmoc-L-Lys(Heptanoyl), Fmoc-HepoK, (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-6- heptanamidohexanoic acid
- Product code:FAA7630
- CAS No.:1528622-16-3
- Formula:C28H36N2O5
- Storage temperature:2-8°C
- Molecular weight:480.6 g/mol
- Purity :min. 98%
- Enantiomeric Purity:min. 99,7%
from $87.50
description
Protected lipoamino acid (LAA), used in the synthesis of modified peptides with increased lipophilicity. HepoK can be genetically encoded for extension of protein half-life in vivo.
references
Genetically Encoding a Lipidated Amino Acid for Extension of Protein Half‐Life in vivo; Prof. Caiyun Fu Qi Chen, Dr. Feng Zheng Liu Yang, Dr. Haorong Li, Qianqian Zhao, Xiumei Wang, Prof. Lei Wang, Dr. Qian Wang; Angew. Chem. Int. Ed. 2019; 58(5): 1392-1396. DOI: 10.1002/anie.201811837.
Hening et al WO 2012088268 A2.
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