Fmoc-L-Glu(Msib)-OH

Chemical name: (2S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-((4-(methylsulfinyl)benzyl)oxy)-5-oxopentanoic acid // Synonyms: Safety-Catch L-Glutamic acid, Fmoc-Glu(Msib)-OH, (2S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-((4-(methylsulfinyl)benzyl)oxy)-glutamic acid,(2S)-2-Fmoc-5-((4-(methylsulfinyl)benzyl)oxy)-5-ox opentanoic acid, (2S)-2-Fmoc-5-((4-(methylsulfinyl

  • Product code:FAA7905
  • CAS No.:2919325-25-8
  • Storage temperature:2-8°C
  • Formula:C28H27NO7S
  • Molecular weight:521.58 g/mol

from $750.00

Grouped product items
Qty Packing unit Price SKU Availability
1 g
$750.00
FAA7905.0001
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description

A Fmoc protected L-Glutamic acid for SPSS, with an Msib protected side chain carboxyl group. The Msib protecting group is removed by reduction of the sulfoxide, followed by acidolysis with TFA.


references

Solid-Phase Peptide Synthesis Using a Four-Dimensional (Safety-Catch) Protecting Group Scheme; S. Noki, E. Brasil, H. Zhang, T. Bruckdorfer, B. de la Torre, F. Albericio; J. Org. Chem. 2022; 87(15): 9443–9453. https://doi.org/10.1021/acs.joc.2c01056


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