Fmoc-L-Glu(MNI)-OH

Chemical name: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-(4-methoxy-7-nitroindolin-1-yl)-5-oxopentanoic acid // Synonyms: Fmoc-L-Glu(4-Methoxy-7-nitroindolin-1-yl)-OH, Fmoc-Glu(Methoxynitroindolinyl)-OH, Fmoc-Glu(MNI)-OH, alpha-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)-2,3-dihydro-4-methoxy-7-nitro-delta-oxo-1H-Indole-1-pentanoic acid

  • Product code:FAA9560
  • CAS No.:1799533-00-8
  • Formula:C29H27N3O8
  • Storage temperature:-20°C
  • Molecular weight:545.45 g/mol

from $375.00

Grouped product items
Qty Packing unit Price SKU Availability
100 mg
$375.00
FAA9560.0100
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250 mg
$750.00
FAA9560.0250
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1 g
$1,875.00
FAA9560.1000
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description

The photosensitive 4-methoxy-7-nitroindoline (MNI) group is used to cage carboxylates. Photolysis is achieved by irradiation at 365 nm.

references

An Fmoc-compatible method for synthesis of peptides containing photocaged aspartic acid or glutamic acid; S. Tang, J.-Y. Cheng, J.-S. Zheng; Tetrahedron Lett. 2015; 56(31): 4582-4585. https://doi.org/10.1016/j.tetlet.2015.06.016

A multiphase transitioning peptide hydrogel for suturing ultrasmall vessels; D. J. Smith, G. A. Brat, S. H. Medina, D. Tong, Y. Huang, J. Grahammer, G. J. Furtmüller, B. C. Oh, K. J. Nagy-Smith, P. Walczal, G. Brandacher, J. P. Schneider; Nat. Nanotech. 2016; 11: 95-102. https://doi.org/10.1038/nnano.2015.238

Biomimetic Heterodimerization of Tetrapeptides to Generate Liquid Crystalline Hydrogel in A Two-Component System; B. Wu, S. Zhao, X. Yang, L. Zhou, Y. Ma, H. Zhang, W. Li, H. Wang; ACS Nano 2022; 16(3): 4126-4138. https://doi.org/10.1021/acsnano.1c09860



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