Mal-L-Dap(Boc)-OPfp

Chemical name: N-alpha-MaleimidoN-beta-t-butyloxycarbonyl-L-2,3-diaminopropionic acid pentafluorophenolate // Synonyms: Mal-Dap(Boc)-OPfp, Mal-Dpr(Boc)-OPfp, 2,3,4,5,6-pentafluorophenyl (2S)-3-{[(tert-butoxy)carbonyl]amino}-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoate

  • Product code:MAA1080
  • CAS No.:1887132-90-2
  • Formula:C18H15F5N2O6
  • Molecular weight:450.31 g/mol
  • Purity :min. 98%

from $118.75

Grouped product items
Qty Packing unit Price SKU Availability
250 mg
$118.75
MAA1080.0250
<10 business days
500 mg
$212.50
MAA1080.0500
<10 business days
1 g
$331.25
MAA1080.1000
<10 business days
5 g
$1,187.50
MAA1080.5000
<10 business days
25 g
$4,750.00
MAA1080.9025
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Safety Data Sheets
description

Mal-Dap(Boc)-OPfp is used in drug conjugate construction leading to more stable conjugates due to Dap neighboring-group assistance. This strategy is widely used in antibody-drug conjugation (ADC).

references

Lyon, Robert; Burke, Patrick; Hunter, Joshua; PCT Int. Appl. (2015), WO 2015057699 A2;

Cong, Qiang; Gangwar, Sanjeev; Rangan, Vangipuram S.; Sung, Mei-Chen; PCT Int. Appl. (2017), WO 2017196598 A1;

Burke, Patrick J.; Courter, Joel; PCT Int. Appl. (2017), WO 2017096311 A1.


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