Fmoc-L-Ile-L-Thr[PSI(Me,Me)Pro]-OH

Chemical name: (4S,5R)-3-(N-(9-Fluorenylmethyloxycarbonyl)-L-isoleucinyl)-2,2,5-trimethyloxazolidine-4-carboxylic acid // Synonyms: Fmoc-Ile-Thr[PSI(Me,Me)Pro]-OH

  • Product code:PSI1190
  • CAS No.:957780-52-8
  • Formula:C28H34N2O6
  • Molecular weight:494.58 g/mol

from $81.25

Grouped product items
Qty Packing unit Price SKU Availability
1 g
$81.25
PSI1190.0001
<10 business days
5 g
$256.25
PSI1190.0005
<10 business days
25 g
$937.50
PSI1190.0025
<10 business days
Safety Data Sheets
description

Pseudoprolines derived from Serine and Threonine have developed to standard building blocks for peptide synthesis since their invention.


references

Pseudo-Prolines as a Molecular Hinge:  Reversible Induction of cis Amide Bonds into Peptide Backbones; P. Dumy, M. Keller, D. E. Ryan, B. Rohwedder, T. Wöhr and M. Mutter; J. Am. Chem. Soc. 1997; 119: 918-925. https://doi.org/10.1021/ja962780


Pseudo-Prolines as a Solubilizing, Structure-Disrupting Protection Technique in Peptide Synthesis; T. Wöhr, F. Wahl, A. Nefzi, B. Rohwedder, T. Sato, X. Sun and M. Mutter; J. Am. Chem. Soc. 1996; 118: 9218-9227. https://doi.org/10.1021/ja961509q


Expediting the Fmoc solid phase synthesis of long peptides through the application of dimethyloxazolidine dipeptides; P. White, J. W. Keyte, K. Bailey and G. Bloomberg; J. Pept. Sci. 2004; 10: 18-26. https://doi.org/10.1002/psc.484


Pseudoprolines as Removable Turn Inducers: Tools for the Cyclization of Small Peptides; D. Skropeta, K. A. Jolliffe, and P. Turner; J. Org. Chem. 2004; 69: 8804-8809. https://doi.org/10.1021/jo0484732

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