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Fmoc-L-Met-L-Ser[PSI(Me,Me)Pro]-OH
Chemical name: (S)-3-(N-(9-Fluorenylmethyloxycarbonyl)-L-methionyl)-2,2-dimethylxoazolidine-4-carboxylic acid // Synonyms: Fmoc-Met-Ser[PSI(Me,Me)Pro]-OH(S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)-L-methionyl)-2,2-dimethyloxazolidine-4-carboxylic acid
- Product code:PSI1620
- Formula:C26H30N2O6S
- Storage temperature:2-8°C
- Molecular weight:498.59 g/mol
from $406.25
description
Pseudoprolines derived from Serine and Threonine have developed to standard building blocks for peptide synthesis since their invention.
references
Pseudo-Prolines as a Molecular Hinge: Reversible Induction of cis Amide Bonds into Peptide Backbones; P. Dumy, M. Keller, D. E. Ryan, B. Rohwedder, T. Wöhr and M. Mutter; J. Am. Chem. Soc. 1997; 119: 918-925. https://doi.org/10.1021/ja962780
Pseudo-Prolines as a Solubilizing, Structure-Disrupting Protection Technique in Peptide Synthesis; T. Wöhr, F. Wahl, A. Nefzi, B. Rohwedder, T. Sato, X. Sun and M. Mutter; J. Am. Chem. Soc. 1996; 118: 9218-9227. https://doi.org/10.1021/ja961509q
Expediting the Fmoc solid phase synthesis of long peptides through the application of dimethyloxazolidine dipeptides; P. White, J. W. Keyte, K. Bailey and G. Bloomberg; J. Pept. Sci. 2004; 10: 18-26. https://doi.org/10.1002/psc.484
Pseudoprolines as Removable Turn Inducers: Tools for the Cyclization of Small Peptides; D. Skropeta, K. A. Jolliffe, and P. Turner; J. Org. Chem. 2004; 69: 8804-8809. https://doi.org/10.1021/jo0484732
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