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MeTz-Bzl-NH2*HCl
Chemical name: Methyltetrazine-benzylamine*HCl // Synonyms: (4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl)methanamine hydrochloride,Compenent: CAS 1345955-28-3
- Product code:RL-2360
- CAS No.:1345955-28-3
- Formula:C10H11N5*HCl
- Storage temperature:-20°C
- Molecular weight:201.23*36.46 g/mol
from $375.00
description
Tetrazine linker for conjugation via Diels-Alder-reaction, i.e. copper-free Click reaction with dienophiles. The amine function can be used to form amid bonds or for alkylation via reductive amination.
references
Bioorthogonal labelling of biomolecules: new functional handles and ligation methods; Marjoke F. Debets, Jan C. M. van Hest and Floris P. J. T. Rutjes; Org. Biomol. Chem. 2013; 11: 6439-6455; DOI:10.1039/c3ob41329b.
Biomedical Applications of Tetrazine Cycloadditions; Neal K. Devaraj and Ralph Weissleder; Acc. Chem. Res. 2011; 44(9): 816-827. DOI: 10.1021/ar200037t.
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