N3Ac-OPhOMe

Chemical name: 4-Methoxyphenyl 2-azidoacetate

  • Product code:RL-3010
  • CAS No.:2546513-31-7
  • Formula:C9H9N3O3
  • Molecular weight:207.19 g/mol

from $281.25

Grouped product items
Qty Packing unit Price SKU Availability
250 mg
$281.25
RL-3010.0250
<10 business days
1 g
$781.25
RL-3010.1000
<10 business days
5 g
$3,125.00
RL-3010.5000
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Safety Data Sheets
description

Methodology for highly selective N-terminal chemical acylation of expressed proteins. This 4-methoxyphenyl ester adds selectively to Gly-His-tags of proteins, while it does not react with epsilon amino functions of surface accessible lysines. Therefore, it expresses a unique possibility to label proteins regiospecific at the Gly-His tag position, enabling a wide application field in chemical biology and for biopharmaceuticals.

references

Selective N-terminal acylation of peptides and proteins with a Gly-His tag sequence; Manuel C. Martos-Maldonado, Christian T. Hjuler, Kasper K. Sørensen, Mikkel B. Thygesen, Jakob E. Rasmussen, Klaus Villadsen, Søren R. Midtgaard, Stefan Kol, Sanne Schoffelen, and Knud J. Jensen; Nature Communications 2018; 9: 3307. DOI: 10.1038/s41467-018-05695-3

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