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Alkyne-SNAP
Chemical name: N-(4-(((2-amino-9H-purin-6-yl)oxy)methyl)benzyl)pent-4-ynamide // Synonyms: Alkyne-Benzylguanine, Alkyne-BG
- Product code:RL-3930
- CAS No.:1104822-07-2
- Formula:C18H18N6O2
- Molecular weight:350.38 g/mol
from $250.00
description
Alkyne conjugated benzylguanine (BG). The BG moiety reacts specifically and rapidly with the so-called SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation.
references
Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand; J. Broichhagen, A. Damijonaitis, J. Levitz, K. R. Sokol, P. Leippe, D. Konrad, E. Y. Isacoff, D. Trauner; ACS Cent Sci. 2015; 1(7): 383-93. https://doi.org/10.1021/acscentsci.5b00260
A Semisynthetic Fluorescent Sensor Protein for Glutamate; M. A. Brun, K.-T. Tan, R. Griss, A. Kielkowska, L. Reymond, K. Johnsson; J. Am. Chem. Soc. 2012; 134(18): 7676-7678. https://doi.org/10.1021/ja3002277
Fura-2FF-based calciumindicator for proteinlabeling; A. A. Ruggiu, M. Bannwarth, K. Johnsson; Org. Biomol. Chem. 2010; 8: 3398-3401. https://doi.org/10.1039/C000158A
Indo-1 Derivatives for Local Calcium Sensing; M. Bannwarth, I. R. Corrêa Jr., M. Sztretye, S. Pouvreau, C. Fellay, A. Aebischer, L. Royer, E. Ríos, K. Johnsson; ACS Chem. Biol. 2009; 4(3): 179-190. https://doi.org/10.1021/cb800258g
Caged Substrates for Protein Labeling and Immobilization; S. Banala, A. Arnold, K. Johnsson; ChemBioChem 2008; 9(1): 38-41. https://doi.org/10.1002/cbic.200700472
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