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Fmoc-L-Asp(OtBu)-MPPA
Nom chimique: N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid beta-t-butyl ester-3-(4-oxymethylphenoxy)propionic acid // Synonymes: (S)-3-(4-(((2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(tert-butoxy)-4-oxobutanoyl)oxy)methyl)phenoxy)propanoic acid,1-[[4-(2-Carboxyethoxy)phenyl]methyl]-4-(1,1-dimethylethyl)-N-[(9H-fluoren-9 -ylmethoxy)carbonyl]-L-aspartate, Fmoc-Asp(OtBu)-M
- n° Art.:LW00402
- n° CAS:864876-94-8
- Formule:C33H35NO9
- Storage temperature:2-8°C
- Masse moléculaire:589,64 g/mol
from 95,00 €
description
This Fmoc-amino acid-MPPA linker serves as precursor for the linkage to e.g. aminomethyl supports by standard coupling procedures. By this method, a low (max 0.5%) and reproducible epimerization level of the C-terminal amino acid in your peptide is guaranteed.
references
Improved approach for anchoring Nalpha-9-fluorenylmethyloxycarbonylamino acids as p-alkoxybenzyl esters in solid-phase peptide synthesis; F. Albericio, G. Barany; Int. J. Peptide. Protein. Res. 1985; 26(1): 92-97. https://doi.org/10.1111/j.1399-3011.1985.tb03182.x.
Amino acid derivatives used as agents bonding to a solid support; NeoMPS S.A. 2005; French Patent Application FR 0402973, International Patent Application WO2005/095332.
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