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Fmoc-L-Glu(OtBu)-MPPA
Nom chimique: N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-glutamic-acid-gamma-t-butyl ester-3-(4-oxymethylphenoxy)propionic acid // Synonymes: (S)-3-(4-(((2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoyl)oxy)methyl)phenoxy)propanoic acid,1-[[4-(2-Carboxyethoxy)phenyl]methyl]-5-(1,1-dimethylethyl)-N-[(9H-fluoren- 9-ylmethoxy)carbonyl]-L-glutamate, Fmoc-Glu(OtBu)-
- n° Art.:LW00602
- n° CAS:864876-95-9
- Formule:C34H37NO9
- Storage temperature:2-8°C
- Masse moléculaire:603,67 g/mol
from 95,00 €
description
This Fmoc-amino acid-MPPA linker serves as precursor for the linkage to e.g. aminomethyl supports by standard coupling procedures. By this method, a low (max 0.5%) and reproducible epimerization level of the C-terminal amino acid in your peptide is guaranteed.
references
Improved approach for anchoring Nalpha-9-fluorenylmethyloxycarbonylamino acids as p-alkoxybenzyl esters in solid-phase peptide synthesis; F. Albericio, G. Barany; Int. J. Peptide. Protein. Res. 1985; 26(1): 92-97. https://doi.org/10.1111/j.1399-3011.1985.tb03182.x
Amino acid derivatives used as agents bonding to a solid support; NeoMPS S.A. 2005; French Patent Application FR 0402973, International Patent Application WO2005/095332.
An Efficient Fmoc Solid-Phase Synthesis of an Amphiphile of the Neuroprotective Agent Glycyl-prolyl-glutamic Acid; P. W. R. Harris, Z.
Amso, G. P. Savage, G. T. Molenaar; Synlett 2014; 25(15): 2221-2224. https://doi.org/10.1055/s-0034-1378539.
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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