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Fmoc-NH-MsbH-COOH
Nom chimique: 5-(2-((((9H-fluoren-9-yl)methoxy)carbonylamino)(4-(methylsulfinyl)phenyl)methyl)-5-(methylsulfinyl)phenoxy)pentanoic acid // Synonymes: Safety-Catch-Acid-Sensitive Linker, 5-(2-((Fmoc-amino)(4-(methylsulfinyl)phenyl)methyl)-5-(methylsulfinyl)phenoxy)pentanoic acid, Fmoc-amino-di(methylsulfinyl)benzhydryl linker,SCAL-Linker
- n° Art.:RL-2260
- n° CAS:147046-64-8
- Formule:C35H35NO7S2
- Storage temperature:-20°C
- Masse moléculaire:645,78 g/mol
from 150,00 €
description
This reagent may be used to build molecules with a free amino group upon release. The pentanoic acid residue can be used to immobilize the SCAL-Linker via an ester or amide on a resin or carrier molecule. The amino group is liberated by reduction of the sulfoxides, followed by acidolysis with TFA.
references
Safety-catch and multiply cleavable linkers in solid-phase synthesis; M. Pátek and M. Lebl; Biopolymers 1998; 47: 353-363. doi:10.1002/(sici)1097-0282(1998)47:5<353::Aid-bip3>3.0.Co;2-i
Safety-catch anchoring linkage for synthesis of peptide amides by Boc/Fmoc strategy; M. Pátek and M. Lebl; Tetrahedron Letters 1991; 32: 3891-3894. doi:10.1016/s0040-4039(00)79406-8
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Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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