Poly-Lysines

Poly-lysines (PLys) are polymers of the canonical amino acid lysine and are characterized by their high charge density caused by the presence of one free amino group per lysine monomer. Thus, this functional group can also serve as an attachment point for further functionalization. PLys are a valuable alternative to PEGs. Poly-lysines are biocompatible and biodegradable, so they do not accumulate in the body or cause an immune response. PLys can be used as carriers for pharmaceuticals, or for the multivalent presentation of molecules.