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PEGylation
PEG derivatives, the pioneers for drug delivery, are available from pure, monodisperse, discrete molecules with short chain lengths to long polydisperse, allowing for regio-specific chemical conjugation with small molecules, proteins, peptides, and biopharmaceuticals through their broad variety of terminal chemical groups available. They can be attached to different positions – most prominent candidates are amino groups of solvent accessible lysines, N-termini, or thiol functions of available cysteines. Rarely used is the C-terminus or carboxylic groups from aspartate and glutamate. Besides, PEG can also serve as spacer or cross linker between two moieties.
![TFP-PEG(4)-[mPEG(11)]3](https://cdn.iris-biotech.de/media/catalog/product/P/E/PEG5030_4.svg?width=240&height=300&store=global&image-type=small_image)
![mal-PEG(4)-[PEG(4)-OMe]3](https://cdn.iris-biotech.de/media/catalog/product/P/E/PEG2310_8.svg?width=240&height=300&store=global&image-type=small_image)
![mal-PEG(4)-[PEG(24)-OMe]3](https://cdn.iris-biotech.de/media/catalog/product/P/E/PEG3420_8.svg?width=240&height=300&store=global&image-type=small_image)
![Mal-PEG(12)-[PEG(11)-Mal]3](https://cdn.iris-biotech.de/media/catalog/product/P/E/PEG7670_11.svg?width=240&height=300&store=global&image-type=small_image)
![Bromoacetamido-PEG(12)-[PEG(11)-bromoacetamide]3](https://cdn.iris-biotech.de/media/catalog/product/P/E/PEG7680_10.svg?width=240&height=300&store=global&image-type=small_image)
