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Blog - Life Sciences - Page 2
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Carbamidomethylated Cysteine as SPPS Building Block
Our building block Fmoc-L-Cys(Cam)-OH enables peptides resembling reduced and carbamido-methylated protein fragments by standard SPPS without error-prone modification reactions.
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PotM: Plant-Derived Cholesterol for LNP Drug Delivery
Plant-derived Cholesterol of high and consistent product quality in accordance with Pharmacopoeia requirements to replace established animal source material in LNP formulation. Read on!
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Fluorogenic Protease Substrates with Enhanced Signal-to-Noise-Ratio
Shine bright like our fluorophores! Learn how our superior fluorogenic protease substrate peptides can enhance your test performance. Click here to gather more information and discover available products!
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PotM: Perfluorobiphenyl Building Blocks for Site-Selective Cysteine Conjugation
Herein, we present functionalized perfluorobiphenyl building blocks which can be used for site-selective π-clamp mediated cysteine conjugation. Read on for more details about this general method!
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PotM: Argpyrimidine Building Block for SPPS
Argpyrimidine is the result of a Maillard Reaction-like nonenzymatic posttranslational modification. You want to investigate the effect of this change on function and stability? Get the building block!
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Choose your Taste – Functionalized Halo/Snap/Clip Substrates
The HaloTag®, SNAP-Tag® and CLIP-TagTM represent versatile tools for the specific, covalent attachment of in principle any molecule of choice to a protein of interest. Discover our substrates!
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PotM: His Tags for the Chemical Modification of Peptides
Jensen et al. developed two methods that use poly-His sequences to direct the highly selective acylation of proteins, either at the N-terminus or at a specific Lys residue. Read on for more information.
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DTT and Spermidine for RNA Buffers and Vaccine Production
See how our “mRNA grade” DTT and Spermidine can support also your nucleic acid production. Read on for more information.
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PotM: Biotin – Desthiobiotin - Iminobiotin
Herein, we present 2-Iminobiotin, a cyclic guanidino analogue of biotin with pH-dependent affinity for avidin, and compare it to biotin and desthiobiotin. Click here for more detailed information.
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Photoswitches
Photoswitches grant the ability to modulate the function of a molecule by effecting a structural change upon irradiation with UV light. Find out about our photoswitchable building blocks and their properties.
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